Transforming Precision Imaging
In-Depth Precision for In Vivo Experiments
Transform your images with the FLUOVIEW™ FV4000MPE multiphoton laser scanning microscope. Advanced imaging technology reveals the details and dynamics of your samples while providing quantitative image data that can enhance your experiments. With our breakthrough SilVIR detector at the core of the system, achieve much lower noise, higher sensitivity, and improved photon resolving capabilities. Coupled with high speed to capture fast dynamics, the system empowers demanding research applications.
Experience the system’s innovations, including:
- Acquire accurate, quantitative image data from the macro scale to subcellular structures
- Gentler, higher-quality live in vivo imaging
- Obtain more information from a single multicolor image
- Monitor neuron and other essential dynamics with high-speed imaging
- Modular design to meet your ever-changing needs
Multiphoton Imaging Made Simple
The FV4000MPE microscope uses our advanced, silicon-based SilVIR™ detector that makes it easier than ever to acquire precise, reproducible data.
SilVIR Next-Generation Detector Technology
The SilVIR detector combines two advanced technologies—a silicon photomultiplier (SiPM) and our patented* fast signal processing design.
- High dynamic range
- Low noise
- No degradation of sensitivity
- Less sensitivity variation among other detectors
*Patent number US11237047
3D image of a live mouse brain from the surface to 900 µm deep using a TruResolution objective. The brighter neural cell body did not saturate thanks to the SilVIR detector’s high dynamic range.
Sample courtesy of: Aoi Gohma and Atsushi Miyawaki, RIKEN CBS-EVIDENT Open Collaboration Center.
Outstanding Multiphoton Images at Depth
The FV4000MPE microscope equipped with a TruResolution objective can efficiently excite fluorochromes deep in your sample by concentrating excitation laser power to achieve a brighter image. The advanced nondescanned (NDD) SilVIR detector has a larger beam diameter to better collect scattered fluorescence emissions from deeper in samples. The upgraded non-descanned detector (NDD) can be configured for a maximum of six channels for multicolor multiphoton imaging. Resonant scanner enables you to acquire large-volume 3D images quickly.
Stitched image of a cleared whole brain captured using 10X objective lens and resonant scanner (512×512 pixels. Z 501 slices, 225 positions). New resonant scanner has the ability to acquire equivalent quality images to galvo scanner in less than a third of the time.
Sample courtesy of: Tetsushi Hoshida and Atsushi Miyawaki, Laboratory for Cell Function Dynamics, RIKEN CBS.
Support and Service You Can Count On
The FV4000MPE system is easy to maintain.
- Semiconductor-based SilVIR detector is stable and durable
- Laser power monitor continuously checks the illumination conditions and makes adjustments to maintain the same laser power
- System admin can view log files to keep track of the service maintenance schedule
We stand behind our products with a commitment to fast service and technical support to help our customers achieve their goals. We offer various support plans to keep your microscope running at peak performance at a predictable cost as well as remote support options, so you don’t need to wait for an engineer or specialist to visit if you’re having an issue.
